Targeting TNF-α with a tetravalent mini-antibody TNF-TeAb

Mengyuan LIU*†, Xiangbin WANG†, Changcheng YIN†, Zhong ZHANG†, Qing LIN†, Yongsu ZHEN§ and Hualiang HUANG†‡1 *Faculty of Life Science, Hubei University, 430062 Wuhan, People’s Republic of China, †Beijing ABT Genetic Engineering Technology Co. Ltd., 102206 Beijing, People’s Republic of China, §The Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Science, 100050 Beijing, People’s Republic of China, and ‡The Institute of Genetics and Developmental Biology, Chinese Academy of Science, 100101 Beijing, People’s Republic of China